5amt: Difference between revisions

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'''Unreleased structure'''


The entry 5amt is ON HOLD
==Intracellular growth locus protein E==
<StructureSection load='5amt' size='340' side='right' caption='[[5amt]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5amt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AMT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AMT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5amu|5amu]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5amt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5amt OCA], [http://pdbe.org/5amt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5amt RCSB], [http://www.ebi.ac.uk/pdbsum/5amt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5amt ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Tularaemia is an uncommon but potentially dangerous zoonotic disease caused by the bacterium Francisella tularensis. As few as ten bacterial cells are sufficient to cause disease in a healthy human, making this one of the most infectious disease agents known. The virulence of this organism is dependent upon a genetic locus known as the Francisella pathogenicity island (FPI), which encodes components of a secretion system that is related to the type VI secretion system. Here, the cloning, expression, purification and preliminary X-ray diffraction statistics of the FPI-encoded protein IglE are presented. This putative lipoprotein is required for intra-macrophage growth and is thought to be a constituent of the periplasmic portion of the type VI-like protein complex that is responsible for the secretion of critical virulence factors in Francisella.


Authors: Robb, C.S., Nano, F.E., Boraston, A.B.
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of intracellular growth locus E (IglE) protein from Francisella tularensis subsp. novicida.,Robb CS, Nano FE, Boraston AB Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Dec 1;66(Pt 12):1596-8., doi: 10.1107/S1744309110034378. Epub 2010 Nov 25. PMID:21139203<ref>PMID:21139203</ref>


Description: Intracellular growth locus protein E
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
[[Category: Unreleased Structures]]
</div>
[[Category: Boraston, A.B]]
<div class="pdbe-citations 5amt" style="background-color:#fffaf0;"></div>
[[Category: Nano, F.E]]
== References ==
[[Category: Robb, C.S]]
<references/>
__TOC__
</StructureSection>
[[Category: Boraston, A B]]
[[Category: Nano, F E]]
[[Category: Robb, C S]]
[[Category: Bacterial secretion system]]
[[Category: Francisella novicida]]
[[Category: Igle]]
[[Category: Lipoprotein]]
[[Category: Transport protein]]
[[Category: Tssj]]
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