5l0o: Difference between revisions
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==IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions== | |||
<StructureSection load='5l0o' size='340' side='right' caption='[[5l0o]], [[Resolution|resolution]] 2.36Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5l0o]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L0O FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i6x|3i6x]]</td></tr> | |||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l0o OCA], [http://pdbe.org/5l0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l0o RCSB], [http://www.ebi.ac.uk/pdbsum/5l0o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l0o ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/IQGA1_HUMAN IQGA1_HUMAN]] Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.<ref>PMID:15695813</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Liu, J]] | [[Category: Liu, J]] | ||
[[Category: Worthylake, D]] | [[Category: Worthylake, D]] | ||
[[Category: Calponin homology]] | |||
[[Category: Disulfide-bonded dimer]] | |||
[[Category: Signaling protein]] | |||
Revision as of 17:11, 3 October 2016
IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions
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