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==Crystal structure of DNPH1 (RCL) with kinetine riboside monophosphate==
==Crystal structure of DNPH1 (RCL) with kinetine riboside monophosphate==
<StructureSection load='4kxn' size='340' side='right' caption='[[4kxn]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='4kxn' size='340' side='right'caption='[[4kxn]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4kxn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KXN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KXN FirstGlance]. <br>
<table><tr><td colspan='2'>[[4kxn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KXN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KXN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6K6:N-(FURAN-2-YLMETHYL)ADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>6K6</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6K6:N-(FURAN-2-YLMETHYL)ADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>6K6</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fyi|4fyi]], [[4kxl|4kxl]], [[4kxm|4kxm]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kxn OCA], [https://pdbe.org/4kxn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kxn RCSB], [https://www.ebi.ac.uk/pdbsum/4kxn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kxn ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dnph1, Rcl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kxn OCA], [http://pdbe.org/4kxn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kxn RCSB], [http://www.ebi.ac.uk/pdbsum/4kxn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kxn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DNPH1_RAT DNPH1_RAT]] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>
[https://www.uniprot.org/uniprot/DNPH1_RAT DNPH1_RAT] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Kaminski, P A]]
[[Category: Rattus norvegicus]]
[[Category: Labesse, G]]
[[Category: Kaminski PA]]
[[Category: Padilla, A]]
[[Category: Labesse G]]
[[Category: Deoxyribonucleoside 5'-monophosphate n-glycosidase]]
[[Category: Padilla A]]
[[Category: Hydrolase]]

Revision as of 09:20, 7 December 2022

Crystal structure of DNPH1 (RCL) with kinetine riboside monophosphate

4kxn, resolution 1.90Å

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