3o2d: Difference between revisions

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==Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody==
==Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody==
<StructureSection load='3o2d' size='340' side='right' caption='[[3o2d]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
<StructureSection load='3o2d' size='340' side='right'caption='[[3o2d]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3o2d]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O2D FirstGlance]. <br>
<table><tr><td colspan='2'>[[3o2d]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O2D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O2D FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o2d OCA], [http://pdbe.org/3o2d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o2d RCSB], [http://www.ebi.ac.uk/pdbsum/3o2d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o2d ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o2d OCA], [https://pdbe.org/3o2d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o2d RCSB], [https://www.ebi.ac.uk/pdbsum/3o2d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o2d ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN]] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.  
[[https://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN]] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[CD4|CD4]]
*[[CD4 3D structures|CD4 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Lk3 transgenic mice]]
[[Category: Chen, B]]
[[Category: Chen, B]]
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