4dlo: Difference between revisions

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==Crystal structure of the GAIN and HormR domains of brain angiogenesis inhibitor 3 (BAI3)==
==Crystal structure of the GAIN and HormR domains of brain angiogenesis inhibitor 3 (BAI3)==
<StructureSection load='4dlo' size='340' side='right' caption='[[4dlo]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='4dlo' size='340' side='right'caption='[[4dlo]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4dlo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DLO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DLO FirstGlance]. <br>
<table><tr><td colspan='2'>[[4dlo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DLO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DLO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dlq|4dlq]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dlo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dlo OCA], [https://pdbe.org/4dlo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dlo RCSB], [https://www.ebi.ac.uk/pdbsum/4dlo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dlo ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAI3, KIAA0550 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dlo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dlo OCA], [http://pdbe.org/4dlo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dlo RCSB], [http://www.ebi.ac.uk/pdbsum/4dlo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dlo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BAI3_HUMAN BAI3_HUMAN]] May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Might be involved in angiogenesis inhibition and suppression of glioblastoma.
[[https://www.uniprot.org/uniprot/AGRB3_HUMAN AGRB3_HUMAN]]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Arac, D]]
[[Category: Large Structures]]
[[Category: Bolliger, M F]]
[[Category: Arac D]]
[[Category: Boucard, A A]]
[[Category: Bolliger MF]]
[[Category: Brunger, A T]]
[[Category: Boucard AA]]
[[Category: Nguyen, J]]
[[Category: Brunger AT]]
[[Category: Soltis, M]]
[[Category: Nguyen J]]
[[Category: Sudhof, T C]]
[[Category: Soltis M]]
[[Category: Autoproteolytic fold]]
[[Category: Sudhof TC]]
[[Category: Extracellular]]
[[Category: Gain domain]]
[[Category: Includes gps motif]]
[[Category: Signaling protein]]
Retrieved from "https://proteopedia.org/4dlo"