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| ==The crystal structure of adenosine deaminase with hypoxanthine bound from Pseudomonas aeruginosa== | | ==The crystal structure of adenosine deaminase with hypoxanthine bound from Pseudomonas aeruginosa== |
| <StructureSection load='3pan' size='340' side='right' caption='[[3pan]], [[Resolution|resolution]] 2.63Å' scene=''> | | <StructureSection load='3pan' size='340' side='right'caption='[[3pan]]' scene=''> |
| == Structural highlights == | | == Structural highlights == |
| <table><tr><td colspan='2'>[[3pan]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PAN FirstGlance]. <br> | | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PAN FirstGlance]. <br> |
| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pan OCA], [https://pdbe.org/3pan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pan RCSB], [https://www.ebi.ac.uk/pdbsum/3pan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pan ProSAT]</span></td></tr> |
| <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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| <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ou8|3ou8]]</td></tr>
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| <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">add, ADD_PSEAE, PA0148 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
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| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_deaminase Adenosine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.4 3.5.4.4] </span></td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pan OCA], [http://pdbe.org/3pan PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pan RCSB], [http://www.ebi.ac.uk/pdbsum/3pan PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pan ProSAT]</span></td></tr> | |
| </table> | | </table> |
| == Function ==
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| [[http://www.uniprot.org/uniprot/ADE_PSEAE ADE_PSEAE]] Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity).
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| ==See Also== | | ==See Also== |
| *[[Adenosine deaminase|Adenosine deaminase]] | | *[[Adenosine deaminase 3D structures|Adenosine deaminase 3D structures]] |
| __TOC__ | | __TOC__ |
| </StructureSection> | | </StructureSection> |
| [[Category: Adenosine deaminase]] | | [[Category: Large Structures]] |
| [[Category: Burley, S K]] | | [[Category: Burley SK]] |
| [[Category: Structural genomic]]
| | [[Category: Swaminathan S]] |
| [[Category: Swaminathan, S]] | | [[Category: Zhang Z]] |
| [[Category: Zhang, Z]] | |
| [[Category: Hydrolase]]
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| [[Category: Hypoxanthine]]
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| [[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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| [[Category: PSI, Protein structure initiative]]
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| [[Category: Sgx]]
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