4bof: Difference between revisions
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==Crystal structure of arginine deiminase from group A streptococcus== | ==Crystal structure of arginine deiminase from group A streptococcus== | ||
<StructureSection load='4bof' size='340' side='right' caption='[[4bof]], [[Resolution|resolution]] 2.48Å' scene=''> | <StructureSection load='4bof' size='340' side='right'caption='[[4bof]], [[Resolution|resolution]] 2.48Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4bof]] is a 8 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4bof]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_scarlatinae"_klein_1884 "micrococcus scarlatinae" klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BOF FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Arginine_deiminase Arginine deiminase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.6 3.5.3.6] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bof OCA], [https://pdbe.org/4bof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bof RCSB], [https://www.ebi.ac.uk/pdbsum/4bof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bof ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/ARCA_STRPY ARCA_STRPY]] Antitumor protein. Has a powerful and dose-dependent inhibitory effect on antigen, superantigen, or mitogen-stimulated human peripheral blood mononuclear cell (PBMC) proliferation. It may inhibit cell proliferation by arresting cell cycle and inducing apoptosis (By similarity).[HAMAP-Rule:MF_00242] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Micrococcus scarlatinae klein 1884]] | [[Category: Micrococcus scarlatinae klein 1884]] | ||
[[Category: Arginine deiminase]] | [[Category: Arginine deiminase]] | ||
[[Category: Large Structures]] | |||
[[Category: Aquilina, J A]] | [[Category: Aquilina, J A]] | ||
[[Category: Batzloff, M R]] | [[Category: Batzloff, M R]] | ||
