3v8h: Difference between revisions

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==Crystal structure of Thymidylate Synthase from Burkholderia thailandensis==
==Crystal structure of Thymidylate Synthase from Burkholderia thailandensis==
<StructureSection load='3v8h' size='340' side='right' caption='[[3v8h]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='3v8h' size='340' side='right'caption='[[3v8h]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3v8h]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Burta Burta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V8H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V8H FirstGlance]. <br>
<table><tr><td colspan='2'>[[3v8h]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Burta Burta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V8H FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">thyA, BTH_I1680 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=271848 BURTA])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">thyA, BTH_I1680 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=271848 BURTA])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v8h OCA], [http://pdbe.org/3v8h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3v8h RCSB], [http://www.ebi.ac.uk/pdbsum/3v8h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3v8h ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v8h OCA], [https://pdbe.org/3v8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v8h RCSB], [https://www.ebi.ac.uk/pdbsum/3v8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v8h ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q2SXY2_BURTA Q2SXY2_BURTA]] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).[HAMAP-Rule:MF_00008]  
[[https://www.uniprot.org/uniprot/Q2SXY2_BURTA Q2SXY2_BURTA]] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).[HAMAP-Rule:MF_00008]  
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Thymidylate synthase|Thymidylate synthase]]
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Burta]]
[[Category: Burta]]
[[Category: Large Structures]]
[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Ssgcid]]
[[Category: Ssgcid]]
[[Category: Transferase]]
[[Category: Transferase]]