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==Crystal structure of Marburg virus VP35 RNA binding domain==
==Crystal structure of Marburg virus VP35 RNA binding domain==
<StructureSection load='4gh9' size='340' side='right' caption='[[4gh9]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='4gh9' size='340' side='right'caption='[[4gh9]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4gh9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lake_victoria_marburgvirus_(strain_musoke-80) Lake victoria marburgvirus (strain musoke-80)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GH9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GH9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4gh9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Marburg_virus_-_Musoke,_Kenya,_1980 Marburg virus - Musoke, Kenya, 1980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GH9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GH9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ks8|3ks8]], [[3fke|3fke]], [[3l2a|3l2a]], [[3l26|3l26]], [[3l25|3l25]], [[4gha|4gha]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gh9 OCA], [https://pdbe.org/4gh9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gh9 RCSB], [https://www.ebi.ac.uk/pdbsum/4gh9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gh9 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VP35 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33727 Lake Victoria marburgvirus (strain Musoke-80)])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gh9 OCA], [http://pdbe.org/4gh9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gh9 RCSB], [http://www.ebi.ac.uk/pdbsum/4gh9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gh9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VP35_MABVM VP35_MABVM]] Acts as a polymerase cofactor in the RNA polymerase transcription and replication complex.  
[https://www.uniprot.org/uniprot/VP35_MABVM VP35_MABVM] Acts as a polymerase cofactor in the RNA polymerase transcription and replication complex.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bale, S]]
[[Category: Large Structures]]
[[Category: Bornholdt, Z A]]
[[Category: Marburg virus - Musoke, Kenya, 1980]]
[[Category: Halfmann, P]]
[[Category: Bale S]]
[[Category: Jean-Philippe, J]]
[[Category: Bornholdt ZA]]
[[Category: Kawaoka, Y]]
[[Category: Halfmann P]]
[[Category: Kimberlin, C K]]
[[Category: Jean-Philippe J]]
[[Category: Kroon, G J.A]]
[[Category: Kawaoka Y]]
[[Category: Kunert, J]]
[[Category: Kimberlin CK]]
[[Category: MacRae, I J]]
[[Category: Kroon GJA]]
[[Category: Saphire, E O]]
[[Category: Kunert J]]
[[Category: Wilson, I A]]
[[Category: MacRae IJ]]
[[Category: Zandonatti, M A]]
[[Category: Saphire EO]]
[[Category: Double stranded viral rna]]
[[Category: Wilson IA]]
[[Category: Interferon inhibition]]
[[Category: Zandonatti MA]]
[[Category: Rna binding protein]]
[[Category: Viral polymerase]]
[[Category: Viral protein]]
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