4n7u: Difference between revisions

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==Crystal Structure of Intracellular B30.2 Domain of BTN3A1 in Complex with CHDMAPP==
==Crystal Structure of Intracellular B30.2 Domain of BTN3A1 in Complex with CHDMAPP==
<StructureSection load='4n7u' size='340' side='right' caption='[[4n7u]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
<StructureSection load='4n7u' size='340' side='right'caption='[[4n7u]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4n7u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N7U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N7U FirstGlance]. <br>
<table><tr><td colspan='2'>[[4n7u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N7U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N7U FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2JA:[(E)-4-METHYL-5-OXIDANYL-PENT-3-ENYL]-PHOSPHONOOXY-PHOSPHINIC+ACID'>2JA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2JA:[(E)-4-METHYL-5-OXIDANYL-PENT-3-ENYL]-PHOSPHONOOXY-PHOSPHINIC+ACID'>2JA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4n7i|4n7i]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n7u OCA], [https://pdbe.org/4n7u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n7u RCSB], [https://www.ebi.ac.uk/pdbsum/4n7u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n7u ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BTF5, BTN3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n7u OCA], [http://pdbe.org/4n7u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4n7u RCSB], [http://www.ebi.ac.uk/pdbsum/4n7u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4n7u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BT3A1_HUMAN BT3A1_HUMAN]] Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.<ref>PMID:21113407</ref> <ref>PMID:21918970</ref> <ref>PMID:22767497</ref> <ref>PMID:22846996</ref>
[https://www.uniprot.org/uniprot/BT3A1_HUMAN BT3A1_HUMAN] Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.<ref>PMID:21113407</ref> <ref>PMID:21918970</ref> <ref>PMID:22767497</ref> <ref>PMID:22846996</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Adams, E J]]
[[Category: Large Structures]]
[[Category: Sandstrom, A]]
[[Category: Adams EJ]]
[[Category: B30 2]]
[[Category: Sandstrom A]]
[[Category: Butyrophilin]]
[[Category: Cd277]]
[[Category: Phosphoantigen]]
[[Category: Pry/spry]]
[[Category: Signaling protein]]