4ic9: Difference between revisions

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==Crystal structure of the full-length matrix subunit (p15) of the Feline Immunodeficiency Virus (FIV) Gag polyprotein==
==Crystal structure of the full-length matrix subunit (p15) of the Feline Immunodeficiency Virus (FIV) Gag polyprotein==
<StructureSection load='4ic9' size='340' side='right' caption='[[4ic9]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4ic9' size='340' side='right'caption='[[4ic9]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ic9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fiv Fiv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IC9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ic9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Feline_immunodeficiency_virus_(isolate_Petaluma) Feline immunodeficiency virus (isolate Petaluma)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IC9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ica|4ica]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ic9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ic9 OCA], [https://pdbe.org/4ic9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ic9 RCSB], [https://www.ebi.ac.uk/pdbsum/4ic9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ic9 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FIV Gag, gag ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11674 FIV])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ic9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ic9 OCA], [http://pdbe.org/4ic9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ic9 RCSB], [http://www.ebi.ac.uk/pdbsum/4ic9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ic9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GAG_FIVPE GAG_FIVPE]] Matrix protein p15 forms the outer shell of the core of the virus, lining the inner surface of the viral membrane (By similarity).  Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity).  Nucleocapsid protein p13 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).  
[https://www.uniprot.org/uniprot/GAG_FIVPE GAG_FIVPE] Matrix protein p15 forms the outer shell of the core of the virus, lining the inner surface of the viral membrane (By similarity).  Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity).  Nucleocapsid protein p13 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fiv]]
[[Category: Large Structures]]
[[Category: Gouet, P]]
[[Category: Gouet P]]
[[Category: Guillon, C]]
[[Category: Guillon C]]
[[Category: Perez, M]]
[[Category: Perez M]]
[[Category: Robert, X]]
[[Category: Robert X]]
[[Category: Serriere, J]]
[[Category: Serriere J]]
[[Category: P15]]
[[Category: Retroviral matrix protein]]
[[Category: Viral protein]]