1lqa: Difference between revisions
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'''TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH''' | '''TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH''' | ||
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[[Category: S2F, Structure 2.Function Project.]] | [[Category: S2F, Structure 2.Function Project.]] | ||
[[Category: Teplyakov, A.]] | [[Category: Teplyakov, A.]] | ||
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[[Category: | [[Category: Structural genomic]] | ||
[[Category: | [[Category: Structure 2 function project]] | ||
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Revision as of 21:10, 2 May 2008
TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH
Overview
BACKGROUND: The protein encoded by the gene ybgI was chosen as a target for a structural genomics project emphasizing the relation of protein structure to function. RESULTS: The structure of the ybgI protein is a toroid composed of six polypeptide chains forming a trimer of dimers. Each polypeptide chain binds two metal ions on the inside of the toroid. CONCLUSION: The toroidal structure is comparable to that of some proteins that are involved in DNA metabolism. The di-nuclear metal site could imply that the specific function of this protein is as a hydrolase-oxidase enzyme.
About this Structure
1LQA is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site., Ladner JE, Obmolova G, Teplyakov A, Howard AJ, Khil PP, Camerini-Otero RD, Gilliland GL, BMC Struct Biol. 2003 Sep 30;3:7. PMID:14519207 Page seeded by OCA on Sat May 3 00:10:22 2008
