4f5z: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:


==Crystal structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant (L95V, A172V).==
==Crystal structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant (L95V, A172V).==
<StructureSection load='4f5z' size='340' side='right' caption='[[4f5z]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
<StructureSection load='4f5z' size='340' side='right'caption='[[4f5z]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4f5z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_mycoides_roseum"_grotenfelt_1889 "bacterium mycoides roseum" grotenfelt 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F5Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4F5Z FirstGlance]. <br>
<table><tr><td colspan='2'>[[4f5z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_rhodochrous Rhodococcus rhodochrous]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F5Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F5Z FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dhaA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1829 "Bacterium mycoides roseum" Grotenfelt 1889])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f5z OCA], [https://pdbe.org/4f5z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f5z RCSB], [https://www.ebi.ac.uk/pdbsum/4f5z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f5z ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f5z OCA], [http://pdbe.org/4f5z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4f5z RCSB], [http://www.ebi.ac.uk/pdbsum/4f5z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4f5z ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH]] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane.  
[https://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 20:


==See Also==
==See Also==
*[[Dehalogenase|Dehalogenase]]
*[[Dehalogenase 3D structures|Dehalogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacterium mycoides roseum grotenfelt 1889]]
[[Category: Large Structures]]
[[Category: Haloalkane dehalogenase]]
[[Category: Rhodococcus rhodochrous]]
[[Category: Kulik, D]]
[[Category: Kulik D]]
[[Category: Kuta-Smatanova, I]]
[[Category: Kuta-Smatanova I]]
[[Category: Rezacova, P]]
[[Category: Rezacova P]]
[[Category: Hydrolase]]
[[Category: Mutation in access tunnel]]

Revision as of 04:36, 7 October 2022

Crystal structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant (L95V, A172V).

4f5z, resolution 1.20Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA