4h2z: Difference between revisions

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==Crystal structure of human GLTP bound with 12:0 monosulfatide==
==Crystal structure of human GLTP bound with 12:0 monosulfatide==
<StructureSection load='4h2z' size='340' side='right' caption='[[4h2z]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='4h2z' size='340' side='right'caption='[[4h2z]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4h2z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H2Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H2Z FirstGlance]. <br>
<table><tr><td colspan='2'>[[4h2z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H2Z FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EIS:N-{(2S,3R,4E)-3-HYDROXY-1-[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]OCTADEC-4-EN-2-YL}DODECANAMIDE'>EIS</scene>, <scene name='pdbligand=MYS:PENTADECANE'>MYS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EIS:N-{(2S,3R,4E)-3-HYDROXY-1-[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]OCTADEC-4-EN-2-YL}DODECANAMIDE'>EIS</scene>, <scene name='pdbligand=MYS:PENTADECANE'>MYS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gh0|4gh0]], [[4gxd|4gxd]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h2z OCA], [https://pdbe.org/4h2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h2z RCSB], [https://www.ebi.ac.uk/pdbsum/4h2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h2z ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLTP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h2z OCA], [http://pdbe.org/4h2z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4h2z RCSB], [http://www.ebi.ac.uk/pdbsum/4h2z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4h2z ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN]] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref>
[https://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Malinina, L]]
[[Category: Large Structures]]
[[Category: Ochoa-Lizarralde, B]]
[[Category: Malinina L]]
[[Category: Samygina, V R]]
[[Category: Ochoa-Lizarralde B]]
[[Category: Gltp-fold]]
[[Category: Samygina VR]]
[[Category: Lipid transport]]
Retrieved from "https://proteopedia.org/4h2z"