4b4z: Difference between revisions
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==Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor== | ==Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor== | ||
<StructureSection load='4b4z' size='340' side='right' caption='[[4b4z]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='4b4z' size='340' side='right'caption='[[4b4z]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4b4z]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4b4z]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinomadura_sp._r39 Actinomadura sp. r39]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B4Z FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BSF:{[(BENZYLSULFONYL)AMINO]METHYL}BORONIC+ACID'>BSF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BSF:{[(BENZYLSULFONYL)AMINO]METHYL}BORONIC+ACID'>BSF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w79|1w79]], [[1w8q|1w8q]], [[1w8y|1w8y]], [[2vgj|2vgj]], [[2vgk|2vgk]], [[2wke|2wke]], [[2xdm|2xdm]], [[2xk1|2xk1]], [[2xln|2xln]], [[2y4a|2y4a]], [[2y55|2y55]], [[2y59|2y59]], [[3zvt|3zvt]], [[3zvw|3zvw]], [[4b4x|4b4x]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w79|1w79]], [[1w8q|1w8q]], [[1w8y|1w8y]], [[2vgj|2vgj]], [[2vgk|2vgk]], [[2wke|2wke]], [[2xdm|2xdm]], [[2xk1|2xk1]], [[2xln|2xln]], [[2y4a|2y4a]], [[2y55|2y55]], [[2y59|2y59]], [[3zvt|3zvt]], [[3zvw|3zvw]], [[4b4x|4b4x]]</td></tr> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/DAC_ACTSP DAC_ACTSP]] Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. | [[http://www.uniprot.org/uniprot/DAC_ACTSP DAC_ACTSP]] Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. | ||
==See Also== | |||
*[[Carboxypeptidase|Carboxypeptidase]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Actinomadura sp. r39]] | ||
[[Category: Large Structures]] | |||
[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]] | [[Category: Serine-type D-Ala-D-Ala carboxypeptidase]] | ||
[[Category: Cannella, S E]] | [[Category: Cannella, S E]] | ||
Revision as of 13:11, 13 March 2019
Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor
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