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==A complex of GlpG with isocoumarin inhibitor covalently bonded to serine 201 and histidine 150==
==A complex of GlpG with isocoumarin inhibitor covalently bonded to serine 201 and histidine 150==
<StructureSection load='3zeb' size='340' side='right' caption='[[3zeb]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3zeb' size='340' side='right'caption='[[3zeb]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zeb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZEB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZEB FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zeb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZEB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZEB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SV1:2-PHENYLETHYL+2-(4-AZANYL-2-METHANOYL-PHENYL)ETHANOATE'>SV1</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SV1:2-PHENYLETHYL+2-(4-AZANYL-2-METHANOYL-PHENYL)ETHANOATE'>SV1</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zeb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zeb OCA], [http://pdbe.org/3zeb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zeb RCSB], [http://www.ebi.ac.uk/pdbsum/3zeb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zeb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zeb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zeb OCA], [https://pdbe.org/3zeb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zeb RCSB], [https://www.ebi.ac.uk/pdbsum/3zeb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zeb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>   
[[https://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>   
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Ecobd]]
[[Category: Ecobd]]
[[Category: Large Structures]]
[[Category: Rhomboid protease]]
[[Category: Rhomboid protease]]
[[Category: Brouwer, A J]]
[[Category: Brouwer, A J]]
Retrieved from "https://proteopedia.org/3zeb"