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==Crystal structure of PX domain of human sorting nexin SNX27==
==Crystal structure of PX domain of human sorting nexin SNX27==
<StructureSection load='4has' size='340' side='right' caption='[[4has]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
<StructureSection load='4has' size='340' side='right'caption='[[4has]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4has]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HAS FirstGlance]. <br>
<table><tr><td colspan='2'>[[4has]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HAS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SNX27, KIAA0488, My014 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4has FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4has OCA], [https://pdbe.org/4has PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4has RCSB], [https://www.ebi.ac.uk/pdbsum/4has PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4has ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4has FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4has OCA], [http://pdbe.org/4has PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4has RCSB], [http://www.ebi.ac.uk/pdbsum/4has PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4has ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SNX27_HUMAN SNX27_HUMAN]] Involved in endocytic trafficking (By similarity). In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes (By similarity).<ref>PMID:17351151</ref>
[https://www.uniprot.org/uniprot/SNX27_HUMAN SNX27_HUMAN] Involved in endocytic trafficking (By similarity). In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes (By similarity).<ref>PMID:17351151</ref>  


==See Also==
==See Also==
*[[Sorting nexin|Sorting nexin]]
*[[Sorting nexin 3D structures|Sorting nexin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Allerston, C]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C]]
[[Category: Allerston C]]
[[Category: Bountra, C]]
[[Category: Arrowsmith C]]
[[Category: Burgess-Brown, N]]
[[Category: Bountra C]]
[[Category: Delft, F von]]
[[Category: Burgess-Brown N]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Froese, D S]]
[[Category: Froese DS]]
[[Category: Kiyani, W]]
[[Category: Kiyani W]]
[[Category: Krojer, T]]
[[Category: Krojer T]]
[[Category: Structural genomic]]
[[Category: Strain-Damerell C]]
[[Category: Strain-Damerell, C]]
[[Category: Yue WW]]
[[Category: Yue, W W]]
[[Category: Von Delft F]]
[[Category: Protein transport]]
[[Category: Px domain]]
[[Category: Sgc]]

Revision as of 08:07, 3 November 2022

Crystal structure of PX domain of human sorting nexin SNX27

4has, resolution 1.74Å

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