4izw: Difference between revisions

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==The E41L mutant of the amidase from Nesterenkonia sp. AN1 showing covalent addition of the acetamide moiety of fluoroacetamide at the active site cysteine==
==The E41L mutant of the amidase from Nesterenkonia sp. AN1 showing covalent addition of the acetamide moiety of fluoroacetamide at the active site cysteine==
<StructureSection load='4izw' size='340' side='right' caption='[[4izw]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='4izw' size='340' side='right'caption='[[4izw]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4izw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nesterenkonia_sp._10004 Nesterenkonia sp. 10004]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IZW FirstGlance]. <br>
<table><tr><td colspan='2'>[[4izw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nesterenkonia_sp._10004 Nesterenkonia sp. 10004]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IZW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IZW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACM:ACETAMIDE'>ACM</scene>, <scene name='pdbligand=FTM:2-FLUOROACETAMIDE'>FTM</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACM:ACETAMIDE'>ACM</scene>, <scene name='pdbligand=FTM:2-FLUOROACETAMIDE'>FTM</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hkx|3hkx]], [[4izs|4izs]], [[4izt|4izt]], [[4izu|4izu]], [[4izv|4izv]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4izw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4izw OCA], [https://pdbe.org/4izw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4izw RCSB], [https://www.ebi.ac.uk/pdbsum/4izw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4izw ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Nit2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=501897 Nesterenkonia sp. 10004])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Amidase Amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.4 3.5.1.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4izw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4izw OCA], [http://pdbe.org/4izw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4izw RCSB], [http://www.ebi.ac.uk/pdbsum/4izw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4izw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/D0VWZ1_9MICC D0VWZ1_9MICC]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Amidase]]
[[Category: Large Structures]]
[[Category: Nesterenkonia sp. 10004]]
[[Category: Nesterenkonia sp. 10004]]
[[Category: Kimani, S W]]
[[Category: Kimani SW]]
[[Category: Sewell, B T]]
[[Category: Sewell BT]]
[[Category: Acetamide]]
[[Category: Active site]]
[[Category: Fluoroacetamide]]
[[Category: Hydrolase]]
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