3u00: Difference between revisions
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==Crystal structure of wild-type onconase at 1.65 A resolution== | ==Crystal structure of wild-type onconase at 1.65 A resolution== | ||
<StructureSection load='3u00' size='340' side='right' caption='[[3u00]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='3u00' size='340' side='right'caption='[[3u00]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3u00]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3u00]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Litpi Litpi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U00 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3phn|3phn]], [[3hg6|3hg6]], [[1onc|1onc]], [[3u01|3u01]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3phn|3phn]], [[3hg6|3hg6]], [[1onc|1onc]], [[3u01|3u01]]</div></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u00 OCA], [https://pdbe.org/3u00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u00 RCSB], [https://www.ebi.ac.uk/pdbsum/3u00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u00 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/RNP30_RANPI RNP30_RANPI]] Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Litpi]] | [[Category: Litpi]] | ||
[[Category: Kurpiewska, K]] | [[Category: Kurpiewska, K]] | ||
Revision as of 05:52, 13 July 2022
Crystal structure of wild-type onconase at 1.65 A resolution
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