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==Structural Basis for Dual-inhibition Mechanism of a Non-classical Kazal-type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin==
==Structural Basis for Dual-inhibition Mechanism of a Non-classical Kazal-type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin==
<StructureSection load='3qtl' size='340' side='right' caption='[[3qtl]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='3qtl' size='340' side='right'caption='[[3qtl]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3qtl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"clostridium_licheniforme"_weigmann_1898 "clostridium licheniforme" weigmann 1898] and [http://en.wikipedia.org/wiki/Carro Carro]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QTL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QTL FirstGlance]. <br>
<table><tr><td colspan='2'>[[3qtl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"clostridium_licheniforme"_weigmann_1898 "clostridium licheniforme" weigmann 1898] and [https://en.wikipedia.org/wiki/Carro Carro]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QTL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QTL FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aprE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1402 "Clostridium licheniforme" Weigmann 1898]), SPI-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6848 CARRO])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aprE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1402 "Clostridium licheniforme" Weigmann 1898]), SPI-1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6848 CARRO])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Subtilisin Subtilisin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.62 3.4.21.62] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Subtilisin Subtilisin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.62 3.4.21.62] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qtl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qtl OCA], [http://pdbe.org/3qtl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3qtl RCSB], [http://www.ebi.ac.uk/pdbsum/3qtl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3qtl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qtl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qtl OCA], [https://pdbe.org/3qtl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qtl RCSB], [https://www.ebi.ac.uk/pdbsum/3qtl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qtl ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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[[Category: Clostridium licheniforme weigmann 1898]]
[[Category: Clostridium licheniforme weigmann 1898]]
[[Category: Carro]]
[[Category: Carro]]
[[Category: Large Structures]]
[[Category: Subtilisin]]
[[Category: Subtilisin]]
[[Category: Shenoy, R T]]
[[Category: Shenoy, R T]]
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