4lla: Difference between revisions
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==Crystal structure of D3D4 domain of the LILRB2 molecule== | ==Crystal structure of D3D4 domain of the LILRB2 molecule== | ||
<StructureSection load='4lla' size='340' side='right' caption='[[4lla]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='4lla' size='340' side='right'caption='[[4lla]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4lla]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4lla]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LLA FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lla OCA], [https://pdbe.org/4lla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lla RCSB], [https://www.ebi.ac.uk/pdbsum/4lla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lla ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/LIRB2_HUMAN LIRB2_HUMAN] Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.<ref>PMID:9548455</ref> <ref>PMID:9842885</ref> <ref>PMID:11875462</ref> <ref>PMID:12853576</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 19: | Line 17: | ||
</div> | </div> | ||
<div class="pdbe-citations 4lla" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4lla" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Leukocyte immunoglobulin-like receptor|Leukocyte immunoglobulin-like receptor]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Gao | [[Category: Large Structures]] | ||
[[Category: Liu | [[Category: Gao GF]] | ||
[[Category: Nam | [[Category: Liu J]] | ||
[[Category: Qi | [[Category: Nam G]] | ||
[[Category: Ryu | [[Category: Qi J]] | ||
[[Category: Shi | [[Category: Ryu M]] | ||
[[Category: Song | [[Category: Shi Y]] | ||
[[Category: Wang | [[Category: Song H]] | ||
[[Category: Yan | [[Category: Wang Q]] | ||
[[Category: Yan J]] | |||
