1mov: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:1mov.gif|left|200px]] | [[Image:1mov.gif|left|200px]] | ||
<!-- | |||
The line below this paragraph, containing "STRUCTURE_1mov", creates the "Structure Box" on the page. | |||
You may change the PDB parameter (which sets the PDB file loaded into the applet) | |||
or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |||
| | or leave the SCENE parameter empty for the default display. | ||
| | --> | ||
{{STRUCTURE_1mov| PDB=1mov | SCENE= }} | |||
}} | |||
'''Crystal structure of Coral protein mutant''' | '''Crystal structure of Coral protein mutant''' | ||
| Line 33: | Line 30: | ||
[[Category: Prescott, M.]] | [[Category: Prescott, M.]] | ||
[[Category: Rossjohn, J.]] | [[Category: Rossjohn, J.]] | ||
[[Category: | [[Category: Chromophore]] | ||
[[Category: | [[Category: Coral pigment]] | ||
[[Category: | [[Category: Fluorescent conversion mutant]] | ||
[[Category: | [[Category: Rtms5]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 01:32:03 2008'' | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | |||
Revision as of 22:32, 2 May 2008
Crystal structure of Coral protein mutant
Overview
Reef-building corals contain host pigments, termed pocilloporins, that function to regulate the light environment of their resident microalgae by acting as a photoprotectant in excessive sunlight. We have determined the crystal structure of an intensely blue, nonfluorescent pocilloporin to 2.2 A resolution and a genetically engineered fluorescent variant to 2.4 A resolution. The pocilloporin chromophore structure adopts a markedly different conformation in comparison with the DsRed chromophore, despite the chromophore sequences (Gln-Tyr-Gly) being identical; the tyrosine ring of the pocilloporin chromophore is noncoplanar and in the trans configuration. Furthermore, the fluorescent variant adopted a noncoplanar chromophore conformation. The data presented here demonstrates that the conformation of the chromophore is highly dependent on its immediate environment.
About this Structure
1MOV is a Single protein structure of sequence from Montipora efflorescens. Full crystallographic information is available from OCA.
Reference
The 2.2 A crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation., Prescott M, Ling M, Beddoe T, Oakley AJ, Dove S, Hoegh-Guldberg O, Devenish RJ, Rossjohn J, Structure. 2003 Mar;11(3):275-84. PMID:12623015 Page seeded by OCA on Sat May 3 01:32:03 2008
