3q5c

Crystal structure of four-way junction with sticky end

spinqualitylabelsall models 3q5c, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3q5c is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed We report here the crystal structure of the partially self-complementary decameric sequence d(CGGCGGCCGC), which self assembles to form a four-way junction with sticky ends. Each junction binds to four others through Watson-Crick base pairing at the sticky ends to form a rhombic structure. The rhombuses bind to each other and form two dimensional tiles. The tiles stack to form the crystal. The crystal diffracted in the space group P1 to a resolution of 2.5A. The junction has the anti-parallel stacked-X conformation like other junction structures, though the formation of the rhombic net noticeably alters the details of the junction geometry. The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice.,Venkadesh S, Mandal PK, Gautham N Biochem Biophys Res Commun. 2011 Apr 15;407(3):548-51. Epub 2011 Mar 16. PMID:21419105 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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