4ewp: Difference between revisions

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==Crystal structure of FabH from Micrococcus luteus==
==Crystal structure of FabH from Micrococcus luteus==
<StructureSection load='4ewp' size='340' side='right' caption='[[4ewp]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4ewp' size='340' side='right'caption='[[4ewp]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ewp]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Miclc Miclc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EWP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EWP FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ewp]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Micrococcus_luteus_NCTC_2665 Micrococcus luteus NCTC 2665]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EWP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EWP FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ebd|2ebd]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ewp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ewp OCA], [https://pdbe.org/4ewp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ewp RCSB], [https://www.ebi.ac.uk/pdbsum/4ewp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ewp ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabH, HMPREF0569_0014, Mlut_09310 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=465515 MICLC])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_III Beta-ketoacyl-[acyl-carrier-protein] synthase III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.180 2.3.1.180] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ewp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ewp OCA], [http://pdbe.org/4ewp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ewp RCSB], [http://www.ebi.ac.uk/pdbsum/4ewp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ewp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/C5CAR9_MICLC C5CAR9_MICLC]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids (By similarity).[HAMAP-Rule:MF_01815]  
[https://www.uniprot.org/uniprot/C5CAR9_MICLC C5CAR9_MICLC] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids (By similarity).[HAMAP-Rule:MF_01815]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Acyl carrier protein synthase|Acyl carrier protein synthase]]
*[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Miclc]]
[[Category: Large Structures]]
[[Category: Adams, P D]]
[[Category: Micrococcus luteus NCTC 2665]]
[[Category: Beller, H R]]
[[Category: Adams PD]]
[[Category: Goh, E B]]
[[Category: Beller HR]]
[[Category: Keasling, J D]]
[[Category: Goh E-B]]
[[Category: Pereira, J H]]
[[Category: Keasling JD]]
[[Category: Synthase]]
[[Category: Pereira JH]]
[[Category: Transferase]]