4h8e: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:


==Structure of S. aureus undecaprenyl diphosphate synthase in complex with FPP and sulfate==
==Structure of S. aureus undecaprenyl diphosphate synthase in complex with FPP and sulfate==
<StructureSection load='4h8e' size='340' side='right' caption='[[4h8e]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='4h8e' size='340' side='right'caption='[[4h8e]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4h8e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staan Staan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H8E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H8E FirstGlance]. <br>
<table><tr><td colspan='2'>[[4h8e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H8E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H8E FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4h2j|4h2j]], [[4h2m|4h2m]], [[4h2o|4h2o]], [[4h38|4h38]], [[4h3a|4h3a]], [[4h3c|4h3c]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h8e OCA], [https://pdbe.org/4h8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h8e RCSB], [https://www.ebi.ac.uk/pdbsum/4h8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h8e ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">uppS, SA1103 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158879 STAAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ditrans,polycis-undecaprenyl-diphosphate_synthase_((2E,6E)-farnesyl-_diphosphate_specific) Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl- diphosphate specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.31 2.5.1.31] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h8e OCA], [http://pdbe.org/4h8e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4h8e RCSB], [http://www.ebi.ac.uk/pdbsum/4h8e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4h8e ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ISPT_STAAN ISPT_STAAN]] Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.[HAMAP-Rule:MF_01139]  
[https://www.uniprot.org/uniprot/ISPT_STAAN ISPT_STAAN] Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.[HAMAP-Rule:MF_01139]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 28: Line 25:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Staan]]
[[Category: Large Structures]]
[[Category: Oldfield, E]]
[[Category: Staphylococcus aureus subsp. aureus N315]]
[[Category: Zhu, W]]
[[Category: Oldfield E]]
[[Category: Alpha-helix]]
[[Category: Zhu W]]
[[Category: Cell wall biosynthesis]]
[[Category: Farnesyl diphosphate binding]]
[[Category: Isopentenyl diphosphate binding]]
[[Category: Prenyl transferase]]
[[Category: Transferase-transferase inhibitor complex]]