2xez: Difference between revisions
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== | ==Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors== | ||
<StructureSection load='2xez' size='340' side='right' caption='[[2xez]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='2xez' size='340' side='right' caption='[[2xez]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xez]] is a 1 chain structure | <table><tr><td colspan='2'>[[2xez]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XEZ FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=XEZ:6-(1H-PYRAZOL-3-YL)-3-(1H-PYRAZOL-4-YL)IMIDAZO[1,2-A]PYRAZINE'>XEZ</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=XEZ:6-(1H-PYRAZOL-3-YL)-3-(1H-PYRAZOL-4-YL)IMIDAZO[1,2-A]PYRAZINE'>XEZ</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2brb|2brb]], [[2x8d|2x8d]], [[2wmr|2wmr]], [[2cgv|2cgv]], [[2brn|2brn]], [[2ayp|2ayp]], [[2wmx|2wmx]], [[2cgu|2cgu]], [[1nvs|1nvs]], [[2brm|2brm]], [[1nvq|1nvq]], [[2wmt|2wmt]], [[2cgx|2cgx]], [[2bro|2bro]], [[2c3j|2c3j]], [[2wmw|2wmw]], [[2wmu|2wmu]], [[2brh|2brh]], [[2x8e|2x8e]], [[2c3k|2c3k]], [[1nvr|1nvr]], [[2wmq|2wmq]], [[1zlt|1zlt]], [[2cgw|2cgw]], [[1zys|1zys]], [[1ia8|1ia8]], [[2br1|2br1]], [[2brg|2brg]], [[2wms|2wms]], [[2wmv|2wmv]], [[2x8i|2x8i]], [[2c3l|2c3l]], [[2xf0|2xf0]], [[2xey|2xey]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2brb|2brb]], [[2x8d|2x8d]], [[2wmr|2wmr]], [[2cgv|2cgv]], [[2brn|2brn]], [[2ayp|2ayp]], [[2wmx|2wmx]], [[2cgu|2cgu]], [[1nvs|1nvs]], [[2brm|2brm]], [[1nvq|1nvq]], [[2wmt|2wmt]], [[2cgx|2cgx]], [[2bro|2bro]], [[2c3j|2c3j]], [[2wmw|2wmw]], [[2wmu|2wmu]], [[2brh|2brh]], [[2x8e|2x8e]], [[2c3k|2c3k]], [[1nvr|1nvr]], [[2wmq|2wmq]], [[1zlt|1zlt]], [[2cgw|2cgw]], [[1zys|1zys]], [[1ia8|1ia8]], [[2br1|2br1]], [[2brg|2brg]], [[2wms|2wms]], [[2wmv|2wmv]], [[2x8i|2x8i]], [[2c3l|2c3l]], [[2xf0|2xf0]], [[2xey|2xey]]</td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Addison, G J]] | [[Category: Addison, G J]] | ||
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[[Category: Klair, S]] | [[Category: Klair, S]] | ||
[[Category: Matthews, T P]] | [[Category: Matthews, T P]] | ||
[[Category: | [[Category: McHardy, T]] | ||
[[Category: Reader, J C]] | [[Category: Reader, J C]] | ||
[[Category: Westwood, I M]] | [[Category: Westwood, I M]] | ||
[[Category: VanMontfort, R]] | |||
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Dna repair]] | [[Category: Dna repair]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||