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{{Large structure}}
 
==Phosphonic Arginine Mimetics as Inhibitors of the M17 Aminopeptidases from Plasmodium falciparum==
==Phosphonic Arginine Mimetics as Inhibitors of the M17 Aminopeptidases from Plasmodium falciparum==
<StructureSection load='4k3n' size='340' side='right' caption='[[4k3n]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4k3n' size='340' side='right'caption='[[4k3n]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4k3n]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K3N FirstGlance]. <br>
<table><tr><td colspan='2'>[[4k3n]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K3N FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1OT:{(R)-AMINO[4-(1H-PYRAZOL-1-YL)PHENYL]METHYL}PHOSPHONIC+ACID'>1OT</scene>, <scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=2PE:NONAETHYLENE+GLYCOL'>2PE</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1OT:{(R)-AMINO[4-(1H-PYRAZOL-1-YL)PHENYL]METHYL}PHOSPHONIC+ACID'>1OT</scene>, <scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=2PE:NONAETHYLENE+GLYCOL'>2PE</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LAP, PF14_0439 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k3n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3n OCA], [https://pdbe.org/4k3n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k3n RCSB], [https://www.ebi.ac.uk/pdbsum/4k3n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k3n ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k3n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3n OCA], [http://pdbe.org/4k3n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k3n RCSB], [http://www.ebi.ac.uk/pdbsum/4k3n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k3n ProSAT]</span></td></tr>
</table>
</table>
{{Large structure}}
== Function ==
[https://www.uniprot.org/uniprot/Q8IL11_PLAF7 Q8IL11_PLAF7]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Aminopeptidase|Aminopeptidase]]
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Plaf7]]
[[Category: Large Structures]]
[[Category: McGowan, S]]
[[Category: Plasmodium falciparum 3D7]]
[[Category: Aminopeptidase]]
[[Category: McGowan S]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Leucyl aminopeptidase]]
[[Category: Protease]]
Retrieved from "https://proteopedia.org/4k3n"