4i8o: Difference between revisions

<StructureSection load='4i8o' size='340' side='right'caption='[[4i8o]], [[Resolution|resolution]] 2.10&Aring;' scene=''>

<table><tr><td colspan='2'>[[4i8o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I8O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I8O FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i8o OCA], [https://pdbe.org/4i8o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i8o RCSB], [https://www.ebi.ac.uk/pdbsum/4i8o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i8o ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/RNLA_ECOLI RNLA_ECOLI] Toxic component of a toxin-antitoxin (TA) module. A stable (half-life 27.6 minutes) endoribonuclease that in the absence of cognate antitoxin RnlB causes generalized RNA degradation. Degrades late enterobacteria phage T4 mRNAs, protecting the host against T4 reproduction. Activity is inhibited by cognate antitoxin RnlB and by enterobacteria phage T4 protein Dmd. Targets cyaA mRNA.<ref>PMID:17895580</ref> <ref>PMID:19019153</ref> <ref>PMID:20980243</ref> <ref>PMID:22403819</ref>  

[[Category: Escherichia coli K-12]]

[[Category: Large Structures]]

[[Category: Dong YH]]

[[Category: Gao ZQ]]

[[Category: Wei Y]]

[[Category: Zhang H]]