4i8p: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
Line 1: Line 1:


==Crystal structure of aminoaldehyde dehydrogenase 1a from Zea mays (ZmAMADH1a)==
==Crystal structure of aminoaldehyde dehydrogenase 1a from Zea mays (ZmAMADH1a)==
<StructureSection load='4i8p' size='340' side='right' caption='[[4i8p]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='4i8p' size='340' side='right'caption='[[4i8p]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4i8p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Maize Maize]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I8P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I8P FirstGlance]. <br>
<table><tr><td colspan='2'>[[4i8p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I8P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I8P FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3iwj|3iwj]], [[3iwk|3iwk]], [[4i8q|4i8q]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i8p OCA], [https://pdbe.org/4i8p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i8p RCSB], [https://www.ebi.ac.uk/pdbsum/4i8p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i8p ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AMADH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4577 MAIZE])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aminobutyraldehyde_dehydrogenase Aminobutyraldehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.19 1.2.1.19] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i8p OCA], [http://pdbe.org/4i8p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4i8p RCSB], [http://www.ebi.ac.uk/pdbsum/4i8p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4i8p ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ADH1A_MAIZE ADH1A_MAIZE] Dehydrogenase that catalyzes the oxidation of several aminoaldehydes (PubMed:23408433). Metabolizes and detoxifies aldehyde products of polyamine degradation to non-toxic amino acids (Probable). Catalyzes the oxidation of 4-aminobutanal and 3-aminopropanal to 4-aminobutanoate and beta-alanine, respectively (PubMed:23408433). Catalyzes the oxidation of 4-(trimethylamino)butanal and 4-guanidinobutanal to 4-trimethylammoniobutanoate and 4-guanidinobutanoate, respectively (PubMed:23408433). Catalyzes the oxidation of betaine aldehyde to glycine betaine (PubMed:23408433).<ref>PMID:23408433</ref>  Dehydrogenase that catalyzes the oxidation of several aminoaldehydes (PubMed:21740525). Catalyzes the oxidation of betaine aldehyde to glycine betaine (PubMed:21740525). Catalyzes the oxidation of 4-(trimethylamino)butanal to 4-trimethylammoniobutanoate (PubMed:21740525).<ref>PMID:21740525</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aminobutyraldehyde dehydrogenase]]
[[Category: Large Structures]]
[[Category: Maize]]
[[Category: Zea mays]]
[[Category: Kopecny, D]]
[[Category: Kopecny D]]
[[Category: Morera, S]]
[[Category: Morera S]]
[[Category: Vigouroux, A]]
[[Category: Vigouroux A]]
[[Category: Aldh10 family fold]]
[[Category: Oxidoreductase]]
Retrieved from "https://proteopedia.org/4i8p"