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==Crystal Structure of Vancomycin Resistance D,D-dipeptidase VanXYg in complex with D-Ala-D-Ala phosphinate analog==
==Crystal Structure of Vancomycin Resistance D,D-dipeptidase VanXYg in complex with D-Ala-D-Ala phosphinate analog==
<StructureSection load='4muq' size='340' side='right' caption='[[4muq]], [[Resolution|resolution]] 1.36&Aring;' scene=''>
<StructureSection load='4muq' size='340' side='right'caption='[[4muq]], [[Resolution|resolution]] 1.36&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4muq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MUQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MUQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4muq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MUQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2D8:(2R)-3-[(R)-[(1S)-1-AMINOETHYL](HYDROXY)PHOSPHORYL]-2-METHYLPROPANOIC+ACID'>2D8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LY0:(2R)-3-[(R)-[(1R)-1-AMINOETHYL](HYDROXY)PHOSPHORYL]-2-METHYLPROPANOIC+ACID'>LY0</scene>, <scene name='pdbligand=PE3:3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL'>PE3</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2D8:(2R)-3-[(R)-[(1S)-1-AMINOETHYL](HYDROXY)PHOSPHORYL]-2-METHYLPROPANOIC+ACID'>2D8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LY0:(2R)-3-[(R)-[(1R)-1-AMINOETHYL](HYDROXY)PHOSPHORYL]-2-METHYLPROPANOIC+ACID'>LY0</scene>, <scene name='pdbligand=PE3:3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL'>PE3</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4f78|4f78]], [[4mur|4mur]], [[4mus|4mus]], [[4mut|4mut]], [[4oak|4oak]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4muq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4muq OCA], [https://pdbe.org/4muq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4muq RCSB], [https://www.ebi.ac.uk/pdbsum/4muq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4muq ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vanXYG, vanYG2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1351 "Enterococcus proteiformis" Thiercelin and Jouhaud 1903])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4muq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4muq OCA], [http://pdbe.org/4muq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4muq RCSB], [http://www.ebi.ac.uk/pdbsum/4muq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4muq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9KHL8_ENTFL Q9KHL8_ENTFL]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Enterococcus proteiformis thiercelin and jouhaud 1903]]
[[Category: Enterococcus faecalis]]
[[Category: Anderson, W F]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Anderson WF]]
[[Category: Courvalin, P]]
[[Category: Courvalin P]]
[[Category: Evdokimova, E]]
[[Category: Di Leo R]]
[[Category: Leo, R Di]]
[[Category: Evdokimova E]]
[[Category: Meziane-Cherif, D]]
[[Category: Meziane-Cherif D]]
[[Category: Savchenko, A]]
[[Category: Savchenko A]]
[[Category: Stogios, P J]]
[[Category: Stogios PJ]]
[[Category: Yim, V]]
[[Category: Yim V]]
[[Category: Alpha+beta protein]]
[[Category: Antibiotic resistance]]
[[Category: Csgid]]
[[Category: D-dipeptidase]]
[[Category: Hedgehog/dd-peptidase fold]]
[[Category: Hydrolase]]
[[Category: Merops m15b subfamily]]
[[Category: Metallopeptidase]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Vancomycin resistance]]
[[Category: Zn2+-dependent d]]
Retrieved from "https://proteopedia.org/4muq"