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==Crystal structure of FK506 binding domain of plasmodium VIVAX FKBP35 in complex with D44==
==Crystal structure of FK506 binding domain of plasmodium VIVAX FKBP35 in complex with D44==
<StructureSection load='4j4o' size='340' side='right' caption='[[4j4o]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
<StructureSection load='4j4o' size='340' side='right'caption='[[4j4o]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4j4o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plavs Plavs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J4O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J4O FirstGlance]. <br>
<table><tr><td colspan='2'>[[4j4o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_vivax_Sal-1 Plasmodium vivax Sal-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J4O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J4O FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D44:N-(2-ETHYLPHENYL)-2-(3H-IMIDAZO[4,5-B]PYRIDIN-2-YLSULFANYL)ACETAMIDE'>D44</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D44:N-(2-ETHYLPHENYL)-2-(3H-IMIDAZO[4,5-B]PYRIDIN-2-YLSULFANYL)ACETAMIDE'>D44</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ni6|3ni6]], [[2ki3|2ki3]], [[3ihz|3ihz]], [[4j4n|4j4n]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j4o OCA], [https://pdbe.org/4j4o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j4o RCSB], [https://www.ebi.ac.uk/pdbsum/4j4o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j4o ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PVX_101260 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=126793 PLAVS])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j4o OCA], [http://pdbe.org/4j4o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j4o RCSB], [http://www.ebi.ac.uk/pdbsum/4j4o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j4o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A5K8X6_PLAVS A5K8X6_PLAVS]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Peptidylprolyl isomerase]]
[[Category: Large Structures]]
[[Category: Plavs]]
[[Category: Plasmodium vivax Sal-1]]
[[Category: Harikishore, A]]
[[Category: Harikishore A]]
[[Category: Sreekanth, R]]
[[Category: Sreekanth R]]
[[Category: Yoon, H S]]
[[Category: Yoon HS]]
[[Category: D44]]
[[Category: Fk506]]
[[Category: Fkbp35]]
[[Category: Isomerase-isomerase inhibitor complex]]

Revision as of 21:32, 16 November 2022

Crystal structure of FK506 binding domain of plasmodium VIVAX FKBP35 in complex with D44

4j4o, resolution 1.73Å

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