4e2q: Difference between revisions

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==Crystal Structure of (S)-Ureidoglycine Aminohydrolase from Arabidopsis thaliana==
==Crystal Structure of (S)-Ureidoglycine Aminohydrolase from Arabidopsis thaliana==
<StructureSection load='4e2q' size='340' side='right' caption='[[4e2q]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4e2q' size='340' side='right'caption='[[4e2q]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4e2q]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E2Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E2Q FirstGlance]. <br>
<table><tr><td colspan='2'>[[4e2q]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E2Q FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ylbA, UGLYAH, At4g17050, AT4G17050 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e2q OCA], [https://pdbe.org/4e2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e2q RCSB], [https://www.ebi.ac.uk/pdbsum/4e2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e2q ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e2q OCA], [http://pdbe.org/4e2q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4e2q RCSB], [http://www.ebi.ac.uk/pdbsum/4e2q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4e2q ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/UGHY_ARATH UGHY_ARATH]] Involved in the catabolism of purine nucleotides. Can use (S)-2-ureidoglycine as substrate, but not allantoate. The sequential activity of AAH, UGLYAH and UAH allows a complete purine breakdown without the intermediate generation of urea.<ref>PMID:19935661</ref> <ref>PMID:20038185</ref> <ref>PMID:22493446</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arabidopsis thaliana]]
[[Category: Rhee, S]]
[[Category: Large Structures]]
[[Category: Shin, I]]
[[Category: Rhee S]]
[[Category: Aminohydrolase]]
[[Category: Shin I]]
[[Category: Bi-cupin]]
[[Category: Endoplasmic reticulum]]
[[Category: Hydrolase]]
[[Category: Manganese binding]]