4ctb: Difference between revisions
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==Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor (5R)-8-amino-3-fluoro-5,19-dimethyl-20-oxo-5,18,19,20- tetrahydro-7,11-(azeno)pyrido(2',1':2,3)imidazo(4,5-h)(2,5,11) benzoxadiazacyclotetradecine-14-carbonitrile== | ==Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor (5R)-8-amino-3-fluoro-5,19-dimethyl-20-oxo-5,18,19,20- tetrahydro-7,11-(azeno)pyrido(2',1':2,3)imidazo(4,5-h)(2,5,11) benzoxadiazacyclotetradecine-14-carbonitrile== | ||
<StructureSection load='4ctb' size='340' side='right' caption='[[4ctb]], [[Resolution|resolution]] 1.79Å' scene=''> | <StructureSection load='4ctb' size='340' side='right'caption='[[4ctb]], [[Resolution|resolution]] 1.79Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ctb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CTB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CTB FirstGlance]. <br> | <table><tr><td colspan='2'>[[4ctb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CTB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CTB FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KVC:(5R)-8-AMINO-3-FLUORO-5,19-DIMETHYL-20-OXO-5,18,19,20-TETRAHYDRO-11,7-(AZENO)PYRIDO[2,1 2,3]IMIDAZO[4,5-H][2,5,11]BENZOXADIAZACYCLOTETRADECINE-14-CARBONITRILE'>KVC</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KVC:(5R)-8-AMINO-3-FLUORO-5,19-DIMETHYL-20-OXO-5,18,19,20-TETRAHYDRO-11,7-(AZENO)PYRIDO[2,1 2,3]IMIDAZO[4,5-H][2,5,11]BENZOXADIAZACYCLOTETRADECINE-14-CARBONITRILE'>KVC</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ctc|4ctc]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ctc|4ctc]]</td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4ctb" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4ctb" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Tyrosine kinase|Tyrosine kinase]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Brooun, A]] | [[Category: Brooun, A]] | ||