1nq3: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:1nq3.gif|left|200px]] | [[Image:1nq3.gif|left|200px]] | ||
<!-- | |||
The line below this paragraph, containing "STRUCTURE_1nq3", creates the "Structure Box" on the page. | |||
You may change the PDB parameter (which sets the PDB file loaded into the applet) | |||
or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |||
or leave the SCENE parameter empty for the default display. | |||
--> | |||
{{STRUCTURE_1nq3| PDB=1nq3 | SCENE= }} | |||
}} | |||
'''Crystal structure of the mammalian tumor associated antigen UK114''' | '''Crystal structure of the mammalian tumor associated antigen UK114''' | ||
| Line 30: | Line 27: | ||
[[Category: Mistiniene, E.]] | [[Category: Mistiniene, E.]] | ||
[[Category: Naktinis, V.]] | [[Category: Naktinis, V.]] | ||
[[Category: | [[Category: Crystal structure]] | ||
[[Category: | [[Category: Trimer]] | ||
[[Category: | [[Category: Tumor associated antigen]] | ||
[[Category: | [[Category: Uk114]] | ||
[[Category: | [[Category: Yer057c/yil051c/yjgf protein family]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:50:36 2008'' | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | |||
Revision as of 23:50, 2 May 2008
Crystal structure of the mammalian tumor associated antigen UK114
Overview
The tumour-associated antigen UK114, isolated from goat liver, belongs to the YER057c/YIL051c/YjgF protein family, which has members in both the prokaryotes and eukaryotes. The crystal structure of a mammalian representative, goat UK114, was determined, revealing a trimeric arrangement in the crystal. It was confirmed by ultracentrifugation that UK114 is a trimer in solution. These results are in agreement with the published structures of homologues from unicellular organisms, but contrast with those reported for the rat homologue of UK114, for which a dimeric quaternary structure was proposed.
About this Structure
1NQ3 is a Single protein structure of sequence from Capra hircus. Full crystallographic information is available from OCA.
Reference
Structure and oligomeric state of the mammalian tumour-associated antigen UK114., Deriu D, Briand C, Mistiniene E, Naktinis V, Grutter MG, Acta Crystallogr D Biol Crystallogr. 2003 Sep;59(Pt 9):1676-8. Epub 2003, Aug 19. PMID:12925811 Page seeded by OCA on Sat May 3 02:50:36 2008
