1nzm: Difference between revisions

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[[Image:1nzm.gif|left|200px]]
[[Image:1nzm.gif|left|200px]]


{{Structure
<!--
|PDB= 1nzm |SIZE=350|CAPTION= <scene name='initialview01'>1nzm</scene>
The line below this paragraph, containing "STRUCTURE_1nzm", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=LG1:3,11-DIFLUORO-6,8,13-TRIMETHYL-8H-QUINO[4,3,2-KL]ACRIDIN-13-IUM'>LG1</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY=  
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_1nzm| PDB=1nzm  | SCENE= }}  
|RELATEDENTRY=[[1np9|1NP9]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nzm OCA], [http://www.ebi.ac.uk/pdbsum/1nzm PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nzm RCSB]</span>
}}


'''NMR structure of the parallel-stranded DNA quadruplex d(TTAGGGT)4 complexed with the telomerase inhibitor RHPS4'''
'''NMR structure of the parallel-stranded DNA quadruplex d(TTAGGGT)4 complexed with the telomerase inhibitor RHPS4'''
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==About this Structure==
==About this Structure==
1NZM is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZM OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZM OCA].  


==Reference==
==Reference==
Drug recognition and stabilisation of the parallel-stranded DNA quadruplex d(TTAGGGT)4 containing the human telomeric repeat., Gavathiotis E, Heald RA, Stevens MF, Searle MS, J Mol Biol. 2003 Nov 14;334(1):25-36. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14596797 14596797]
Drug recognition and stabilisation of the parallel-stranded DNA quadruplex d(TTAGGGT)4 containing the human telomeric repeat., Gavathiotis E, Heald RA, Stevens MF, Searle MS, J Mol Biol. 2003 Nov 14;334(1):25-36. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14596797 14596797]
[[Category: Protein complex]]
[[Category: Gavathiotis, E.]]
[[Category: Gavathiotis, E.]]
[[Category: Heald, R A.]]
[[Category: Heald, R A.]]
[[Category: Searle, M S.]]
[[Category: Searle, M S.]]
[[Category: Stevens, M F.G.]]
[[Category: Stevens, M F.G.]]
[[Category: drug-dna interaction]]
[[Category: Drug-dna interaction]]
[[Category: molecular dynamic]]
[[Category: Molecular dynamic]]
[[Category: nmr spectroscopy]]
[[Category: Nmr spectroscopy]]
[[Category: quadruplex dna]]
[[Category: Quadruplex dna]]
[[Category: telomerase inhibition]]
[[Category: Telomerase inhibition]]
[[Category: telomere]]
[[Category: Telomere]]
[[Category: ttagggt repeat]]
[[Category: Ttagggt repeat]]
 
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