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==Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofuranone derivative==
==Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofuranone derivative==
<StructureSection load='3vva' size='340' side='right' caption='[[3vva]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
<StructureSection load='3vva' size='340' side='right'caption='[[3vva]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3vva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trybb Trybb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VVA FirstGlance]. <br>
<table><tr><td colspan='2'>[[3vva]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trybb Trybb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VVA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHW:3-CHLORO-4,6-DIHYDROXY-5-[(2E,6E,8S)-8-HYDROXY-3,7-DIMETHYLNONA-2,6-DIEN-1-YL]-2-METHYLBENZALDEHYDE'>CHW</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=OH:HYDROXIDE+ION'>OH</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CHW:3-CHLORO-4,6-DIHYDROXY-5-[(2E,6E,8S)-8-HYDROXY-3,7-DIMETHYLNONA-2,6-DIEN-1-YL]-2-METHYLBENZALDEHYDE'>CHW</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=OH:HYDROXIDE+ION'>OH</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vv9|3vv9]], [[3w54|3w54]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vv9|3vv9]], [[3w54|3w54]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AOX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5702 TRYBB])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AOX ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5702 TRYBB])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vva OCA], [http://pdbe.org/3vva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vva RCSB], [http://www.ebi.ac.uk/pdbsum/3vva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vva ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vva OCA], [https://pdbe.org/3vva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vva RCSB], [https://www.ebi.ac.uk/pdbsum/3vva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vva ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/AOX_TRYBB AOX_TRYBB]] Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.  
[[https://www.uniprot.org/uniprot/AOX_TRYBB AOX_TRYBB]] Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Trybb]]
[[Category: Trybb]]
[[Category: Aoki, T]]
[[Category: Aoki, T]]
Retrieved from "https://proteopedia.org/3vva"