RmlC: Difference between revisions
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<StructureSection load='2ixc' size='340' side='right' caption='Structure of RmlC complex with dTPD-rhamnose (PDB code [[2ixc]]).' scene=''> | <StructureSection load='2ixc' size='340' side='right' caption='Structure of RmlC complex with dTPD-rhamnose (PDB code [[2ixc]]).' scene=''> | ||
== Function == | == Function == | ||
'''RmlC''' is an enzyme of the dTPD-rhamnose pathway. Deoxy-thymidine diphosphate (dTDP)-L-rhamnose is the precursor of L-rhamnose. L-rhamnose is a sugar component of microbial cell wall and is absent in human<ref>PMID:10802738</ref>. | '''RmlC''' is an epimerase enzyme of the dTPD-rhamnose pathway. Deoxy-thymidine diphosphate (dTDP)-L-rhamnose is the precursor of L-rhamnose. L-rhamnose is a sugar component of microbial cell wall and is absent in human<ref>PMID:10802738</ref>. | ||
== Disease == | == Disease == | ||
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== Structural highlights == | == Structural highlights == | ||
The active site of RmlC contains the reaction product DTDP-L-rhmnose<ref>PMID:17046787</ref>. | |||
</StructureSection> | </StructureSection> | ||
