5ko2: Difference between revisions

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'''Unreleased structure'''


The entry 5ko2 is ON HOLD  until Paper Publication
==Mouse pgp 34 linker deleted mutant Hg derivative==
 
<StructureSection load='5ko2' size='340' side='right' caption='[[5ko2]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
Authors: Xia, D., Esser, L., Zhou, F.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5ko2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KO2 FirstGlance]. <br>
Description: Mouse pgp 34 linker deleted mutant Hg derivative
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kpd|5kpd]], [[5koy|5koy]], [[5kpj|5kpj]], [[5kpi|5kpi]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xenobiotic-transporting_ATPase Xenobiotic-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.44 3.6.3.44] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ko2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ko2 OCA], [http://pdbe.org/5ko2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ko2 RCSB], [http://www.ebi.ac.uk/pdbsum/5ko2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ko2 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Xenobiotic-transporting ATPase]]
[[Category: Esser, L]]
[[Category: Xia, D]]
[[Category: Xia, D]]
[[Category: Zhou, F]]
[[Category: Zhou, F]]
[[Category: Esser, L]]
[[Category: Drug transport]]
[[Category: Hydrolase]]
[[Category: Mercury derivative]]
[[Category: Mouse pgp]]
[[Category: Multidrug resistance]]

Revision as of 18:35, 10 December 2016

Mouse pgp 34 linker deleted mutant Hg derivative

5ko2, resolution 3.30Å

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