1e26: Difference between revisions

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[[Image:1e26.gif|left|200px]]<br />

[[Image:1e26.gif|left|200px]]<br /><applet load="1e26" size="450" color="white" frame="true" align="right" spinBox="true"

<applet load="1e26" size="450" color="white" frame="true" align="right" spinBox="true"

caption="1e26, resolution 2.0Å" />

'''DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.'''<br />

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==About this Structure==

1E26 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii] with NAP and GPB as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] ~~Structure known Active~~ Site: S1. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1E26 OCA].

1E26 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii] with NAP and GPB as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] Known structural/functional Site: <scene name='pdbsite=S1:Nap Binding Site'>S1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1E26 OCA].

==Reference==

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[[Category: thymidylate synthase]]

''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on ~~Mon Nov 5 16~~:04:09 2007''

''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 14:52:07 2007''

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-[[Image:1e26.gif|left|200px]]<br />
+[[Image:1e26.gif|left|200px]]<br /><applet load="1e26" size="450" color="white" frame="true" align="right" spinBox="true"
-<applet load="1e26" size="450" color="white" frame="true" align="right" spinBox="true"
 caption="1e26, resolution 2.0&Aring;" />
 '''DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.'''<br />
@@ Line 8: / Line 7: @@
 ==About this Structure==
-E26 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii] with NAP and GPB as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] Structure known Active Site: S1. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1E26 OCA].
+E26 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii] with NAP and GPB as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] Known structural/functional Site: <scene name='pdbsite=S1:Nap Binding Site'>S1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1E26 OCA].
 ==Reference==
@@ Line 27: / Line 26: @@
 [[Category: thymidylate synthase]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov  5 16:04:09 2007''
+''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 14:52:07 2007''