Transposase: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
Transposase contains a DDE motif in its active site<ref>PMID:18790806</ref> enabling it to coordinate the binding of divalent metal ions. The metal ions affect transposase reactivity. | Transposase contains a DDE motif in its active site<ref>PMID:18790806</ref> enabling it to coordinate the binding of divalent metal ions. The metal ions affect transposase reactivity. The DDE motif is conserved in transposases and retroviral integrases and is essential for their activity. | ||
</StructureSection> | </StructureSection> | ||
