5gu6: Difference between revisions
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==Crystal structure of Human ERp44 form I== | |||
<StructureSection load='5gu6' size='340' side='right' caption='[[5gu6]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5gu6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GU6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GU6 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |||
[[ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5gu7|5gu7]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gu6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gu6 OCA], [http://pdbe.org/5gu6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gu6 RCSB], [http://www.ebi.ac.uk/pdbsum/5gu6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gu6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ERP44_HUMAN ERP44_HUMAN]] Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.<ref>PMID:11847130</ref> <ref>PMID:14517240</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Inaba, K]] | [[Category: Inaba, K]] | ||
[[Category: Watanabe, S]] | [[Category: Watanabe, S]] | ||
[[Category: Chaperone]] | |||
[[Category: Quality control]] | |||
Revision as of 11:41, 12 April 2017
Crystal structure of Human ERp44 form I
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