5k87: Difference between revisions
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==crystal structure of malonate bound to methylaconitate isomerase PrpF from Shewanella oneidensis== | |||
<StructureSection load='5k87' size='340' side='right' caption='[[5k87]], [[Resolution|resolution]] 1.22Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5k87]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sheon Sheon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K87 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K87 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr> | |||
[[Category: | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">prpF, SO_0342 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=211586 SHEON])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k87 OCA], [http://pdbe.org/5k87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k87 RCSB], [http://www.ebi.ac.uk/pdbsum/5k87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k87 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PRPF_SHEON PRPF_SHEON]] Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle II (propionate degradation route). PrpF catalyzes the cis-trans isomerization of 2-methyl-aconitate through a base-catalyzed proton abstraction coupled with a rotation about C2-C3 bond of 2-methyl-aconitate.<ref>PMID:14702315</ref> <ref>PMID:17567742</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Sheon]] | |||
[[Category: Rayment, I]] | |||
[[Category: Wetterhorn, K]] | |||
[[Category: Isomerase]] | |||
[[Category: Prpf methylaconitate isomerase 2-mmc]] | |||