1p44: Difference between revisions

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[[Image:1p44.gif|left|200px]]
[[Image:1p44.gif|left|200px]]


{{Structure
<!--
|PDB= 1p44 |SIZE=350|CAPTION= <scene name='initialview01'>1p44</scene>, resolution 2.7&Aring;
The line below this paragraph, containing "STRUCTURE_1p44", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=GEQ:5-{[4-(9H-FLUOREN-9-YL)PIPERAZIN-1-YL]CARBONYL}-1H-INDOLE'>GEQ</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span>
or leave the SCENE parameter empty for the default display.
|GENE= INHA OR RV1484 OR MT1531 OR MTCY277.05 OR MB1520 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
-->
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0623 FabI], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK07889 PRK07889]</span>
{{STRUCTURE_1p44| PDB=1p44  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p44 OCA], [http://www.ebi.ac.uk/pdbsum/1p44 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1p44 RCSB]</span>
}}


'''Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data'''
'''Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data'''
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==Reference==
==Reference==
Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data., Kuo MR, Morbidoni HR, Alland D, Sneddon SF, Gourlie BB, Staveski MM, Leonard M, Gregory JS, Janjigian AD, Yee C, Musser JM, Kreiswirth B, Iwamoto H, Perozzo R, Jacobs WR Jr, Sacchettini JC, Fidock DA, J Biol Chem. 2003 Jun 6;278(23):20851-9. Epub 2003 Feb 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12606558 12606558]
Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data., Kuo MR, Morbidoni HR, Alland D, Sneddon SF, Gourlie BB, Staveski MM, Leonard M, Gregory JS, Janjigian AD, Yee C, Musser JM, Kreiswirth B, Iwamoto H, Perozzo R, Jacobs WR Jr, Sacchettini JC, Fidock DA, J Biol Chem. 2003 Jun 6;278(23):20851-9. Epub 2003 Feb 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12606558 12606558]
[[Category: Enoyl-[acyl-carrier-protein] reductase (NADH)]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: TBSGC, TB Structural Genomics Consortium.]]
[[Category: TBSGC, TB Structural Genomics Consortium.]]
[[Category: Yee, C.]]
[[Category: Yee, C.]]
[[Category: enoyl-acp reductase]]
[[Category: Enoyl-acp reductase]]
[[Category: inha]]
[[Category: Inha]]
[[Category: inhibitor]]
[[Category: Inhibitor]]
[[Category: protein structure initiative]]
[[Category: Protein structure initiative]]
[[Category: psi]]
[[Category: Psi]]
[[Category: rossmann fold]]
[[Category: Rossmann fold]]
[[Category: short chain dehydrogenase reductase]]
[[Category: Short chain dehydrogenase reductase]]
[[Category: structural genomic]]
[[Category: Structural genomic]]
[[Category: tb structural genomics consortium]]
[[Category: Tb structural genomics consortium]]
[[Category: tbsgc]]
[[Category: Tbsgc]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 04:39:26 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:54:32 2008''