5tia: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "5tia" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of human TDO in complex with Trp, Northeast Structural Genomics Consortium Target HR6161== | |||
<StructureSection load='5tia' size='340' side='right' caption='[[5tia]], [[Resolution|resolution]] 2.44Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5tia]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TIA FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene></td></tr> | |||
[[ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ti9|5ti9]]</td></tr> | ||
[[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan_2,3-dioxygenase Tryptophan 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.11 1.13.11.11] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tia OCA], [http://pdbe.org/5tia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tia RCSB], [http://www.ebi.ac.uk/pdbsum/5tia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tia ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/T23O_HUMAN T23O_HUMAN]] Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Tryptophan 2,3-dioxygenase]] | |||
[[Category: Forouhar, F]] | [[Category: Forouhar, F]] | ||
[[Category: Structural genomic]] | |||
[[Category: Tong, L]] | [[Category: Tong, L]] | ||
[[Category: 3-dioxygenase]] | |||
[[Category: Human tryptophan 2]] | |||
[[Category: Nesg]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Psi-biology]] | |||
