5h2w: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "5h2w" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-340)== | |||
<StructureSection load='5h2w' size='340' side='right' caption='[[5h2w]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5h2w]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H2W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5H2W FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5h2x|5h2x]], [[5h2v|5h2v]]</td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ulp1_peptidase Ulp1 peptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.68 3.4.22.68] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5h2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h2w OCA], [http://pdbe.org/5h2w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h2w RCSB], [http://www.ebi.ac.uk/pdbsum/5h2w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h2w ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/IMA1_YEAST IMA1_YEAST]] Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs (By similarity).<ref>PMID:7565597</ref> <ref>PMID:10913188</ref> <ref>PMID:21075847</ref> [[http://www.uniprot.org/uniprot/ULP1_YEAST ULP1_YEAST]] Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SMT3 to its mature form and deconjugation of SMT3 from targeted proteins. Has an essential role in the G2/M phase of the cell cycle.<ref>PMID:10094048</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Ulp1 peptidase]] | |||
[[Category: Hirano, H]] | |||
[[Category: Matsuura, Y]] | |||
[[Category: Nuclear import]] | |||
[[Category: Protein transport-hydrolase complex]] | |||
Revision as of 19:16, 15 December 2016
Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-340)
| ||||||||||||
