5m62: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5m62 is ~~ON HOLD~~ ~~until Paper Publication~~

==Structure of the Mus musclus Langerin carbohydrate recognition domain in complex with glucose==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5m62]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M62 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M62 FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5k8y|5k8y]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m62 OCA], [http://pdbe.org/5m62 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m62 RCSB], [http://www.ebi.ac.uk/pdbsum/5m62 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m62 ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/CLC4K_MOUSE CLC4K_MOUSE]] Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells.<ref>PMID:11777972</ref> <ref>PMID:18322168</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Aretz, J]]

[[Category: Loll, B]]

[[Category: Rademacher, C]]

[[Category: Wahl, M C]]

[[Category: C-type lectin]]

[[Category: Calcium binding]]

[[Category: Carbohydrate binding protein]]

[[Category: Crd domain]]

[[Category: Glycoprotein]]

[[Category: Immune system]]

[[Category: Lectin]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5m62 is ON HOLD  until Paper Publication
+==Structure of the Mus musclus Langerin carbohydrate recognition domain in complex with glucose==
+<StructureSection load='5m62' size='340' side='right' caption='[[5m62]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5m62]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M62 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M62 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5k8y|5k8y]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m62 OCA], [http://pdbe.org/5m62 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m62 RCSB], [http://www.ebi.ac.uk/pdbsum/5m62 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m62 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CLC4K_MOUSE CLC4K_MOUSE]] Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells.<ref>PMID:11777972</ref> <ref>PMID:18322168</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Aretz, J]]
+[[Category: Loll, B]]
+[[Category: Rademacher, C]]
+[[Category: Wahl, M C]]
+[[Category: C-type lectin]]
+[[Category: Calcium binding]]
+[[Category: Carbohydrate binding protein]]
+[[Category: Crd domain]]
+[[Category: Glycoprotein]]
+[[Category: Immune system]]
+[[Category: Lectin]]