5tkv: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 5tkv is ON HOLD until Paper Publication~~

==X-RAY CRYSTAL STRUCTURE OF THE "CLOSED" CONFORMATION OF CTP-INHIBITED E. COLI CYTIDINE TRIPHOSPHATE (CTP) SYNTHETASE==

~~Authors: Baldwin, E.P., Endrizzi, J.A.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5tkv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TKV OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TKV FirstGlance].

~~Description:~~ X-RAY CRYSTAL STRUCTURE OF THE ""CLOSED"" CONFORMATION OF CTP-INHIBITED E. COLI CYTIDINE TRIPHOSPHATE (CTP) SYNTHETASE

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/CTP_synthase_(glutamine_hydrolyzing) CTP synthase (glutamine hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </td></tr>

[[Category: Endrizzi, J.A]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tkv OCA], [http://pdbe.org/5tkv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tkv RCSB], [http://www.ebi.ac.uk/pdbsum/5tkv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tkv ProSAT]</td></tr>

[[Category: ~~Baldwin, E.P~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/PYRG_ECOLI PYRG_ECOLI]] Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.[HAMAP-Rule:MF_01227]

__TOC__

</StructureSection>

[[Category: Baldwin, E P]]

[[Category: Endrizzi, J A]]

[[Category: Enzyme regulation via polymerization]]

[[Category: Feedback inhibition]]

[[Category: Lyase]]

[[Category: Pyrimidine biosynthesis]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5tkv is ON HOLD  until Paper Publication
+==X-RAY CRYSTAL STRUCTURE OF THE "CLOSED" CONFORMATION OF CTP-INHIBITED E. COLI CYTIDINE TRIPHOSPHATE (CTP) SYNTHETASE==
+<StructureSection load='5tkv' size='340' side='right' caption='[[5tkv]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-Authors: Baldwin, E.P., Endrizzi, J.A.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5tkv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TKV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TKV FirstGlance]. <br>
-Description: X-RAY CRYSTAL STRUCTURE OF THE ""CLOSED"" CONFORMATION OF CTP-INHIBITED E. COLI CYTIDINE TRIPHOSPHATE (CTP) SYNTHETASE
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP_synthase_(glutamine_hydrolyzing) CTP synthase (glutamine hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>
-[[Category: Endrizzi, J.A]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tkv OCA], [http://pdbe.org/5tkv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tkv RCSB], [http://www.ebi.ac.uk/pdbsum/5tkv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tkv ProSAT]</span></td></tr>
-[[Category: Baldwin, E.P]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/PYRG_ECOLI PYRG_ECOLI]] Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.[HAMAP-Rule:MF_01227]
+__TOC__
+</StructureSection>
+[[Category: Baldwin, E P]]
+[[Category: Endrizzi, J A]]
+[[Category: Enzyme regulation via polymerization]]
+[[Category: Feedback inhibition]]
+[[Category: Lyase]]
+[[Category: Pyrimidine biosynthesis]]