Invanz Sandbox: Difference between revisions

'''Hypersensitivity Reactions'''

Patients with a history of anaphylactic reaction after treatment with beta lactam antibiotics, as well as patients affected by multiple allergens are more susceptible to adverse drug reactions after taking Invanz. Before beginning therapy with Invanz, such individuals should consult with an allergist in regards to any hypersensitivity to other beta-lactams, penicillins and cephalosporins.

'''Drug-Resistant Bacteria'''

As with many other antibiotics, extended use of Invanz can lead to the development of drug-resistant bacteria. In order to ensure the effectiveness of the drug, Invanz should only be prescribed to treat a strongly-suspected bacterial infection.  

'''Seizure Potential'''

Although rare, some adult patients treated with the drug experienced seizures. Seizures are most common in patients with central nervous system (CNS) disorders. In case of seizures, anticonvulsant therapy should be instituted or continued in patients with known seizure disorder. The dosage of the drug should also be re-examined and re-adjusted, accordingly.  

'''Interaction with Valproic Acid'''

Valproic acid is used to treat patients with bipolar disorders, to prevent migraines, and for different types of seizures. Taking Invanz lowers the concentration of the valproic acid, therefore increasing the risk of seizures and other diseases used to treat the patient. For patients dependent on valproic acid, Invanz is not recommended <ref>United States National Institutes of Health. Current Medication Information for INVANZ (Ertapenem sodium) injection, powder, lyphilized for solution. http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=33f3b99b-fa82-42e0-26bf-f49891ae3d22 (accessed November 17, 2016)</ref>.