5tjb: Difference between revisions
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The entry | ==I-II linker of TRPML1 channel at pH 4.5== | ||
<StructureSection load='5tjb' size='340' side='right' caption='[[5tjb]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5tjb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TJB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TJB FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tja|5tja]], [[5tjc|5tjc]]</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tjb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tjb OCA], [http://pdbe.org/5tjb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tjb RCSB], [http://www.ebi.ac.uk/pdbsum/5tjb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tjb ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/MCLN1_HUMAN MCLN1_HUMAN]] Mucolipidosis type 4. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/MCLN1_HUMAN MCLN1_HUMAN]] Cation channel probably playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. Could play a major role in Ca(2+) transport regulating lysosomal exocytosis.<ref>PMID:12459486</ref> <ref>PMID:14749347</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Benvin, N M]] | |||
[[Category: Li, H]] | |||
[[Category: Li, M]] | |||
[[Category: Li, X]] | |||
[[Category: Michailidis, I E]] | |||
[[Category: Su, D]] | |||
[[Category: Tong, L]] | |||
[[Category: Wang, S]] | |||
[[Category: Yang, J]] | |||
[[Category: Zhang, W K]] | |||
[[Category: Zhou, X]] | |||
[[Category: Calcium and ph regulation]] | |||
[[Category: Endolysosomal lumen]] | |||
[[Category: Tetramer]] | |||
[[Category: Transport protein]] | |||
Revision as of 23:46, 25 January 2017
I-II linker of TRPML1 channel at pH 4.5
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