5tkq: Difference between revisions
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==Crystal structure of human 3HAO with zinc bound in the active site== | |||
<StructureSection load='5tkq' size='340' side='right' caption='[[5tkq]], [[Resolution|resolution]] 1.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5tkq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TKQ FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxyanthranilate_3,4-dioxygenase 3-hydroxyanthranilate 3,4-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.6 1.13.11.6] </span></td></tr> | ||
[[Category: Toth, E | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tkq OCA], [http://pdbe.org/5tkq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tkq RCSB], [http://www.ebi.ac.uk/pdbsum/5tkq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tkq ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/3HAO_HUMAN 3HAO_HUMAN]] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.<ref>PMID:7514594</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: 3-hydroxyanthranilate 3,4-dioxygenase]] | |||
[[Category: Pidugu, L S]] | |||
[[Category: Toth, E A]] | |||
[[Category: 3-hydroxyanthranilate oxygenase]] | |||
[[Category: Cupin kynurenine pathway]] | |||
[[Category: Oxidoreductase]] | |||
Revision as of 11:47, 12 April 2017
Crystal structure of human 3HAO with zinc bound in the active site
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